Weight Loss5 min read

Understanding GLP-1 Medications: What You Need to Know

Learn about how GLP-1 medications like Semaglutide and Tirzepatide work for weight loss and what to expect from treatment.

Dr. Michael Johnson, DO, ABAARM

January 10, 2026

Medical professional discussing treatment options with patient

What Are GLP-1 Medications?

GLP-1 (glucagon-like peptide-1) receptor agonists have revolutionized the field of medical weight loss. Originally developed for diabetes management, medications like Semaglutide (Wegovy, Ozempic) and Tirzepatide (Mounjaro, Zepbound) have shown remarkable effectiveness for weight management. These injectable medications work by mimicking a hormone naturally produced in your gut.

How Do GLP-1 Medications Work?

GLP-1 medications work through several mechanisms to support weight loss. They signal to your brain that you're full, reducing hunger and food cravings. They also slow gastric emptying, meaning food stays in your stomach longer and helps you feel satisfied with smaller portions. Additionally, these medications help regulate insulin release and blood sugar levels, which can be beneficial for overall metabolic health.

What Results Can You Expect?

Clinical trials have demonstrated impressive and consistent results with GLP-1 medications. Semaglutide users lost an average of 15-20% of their body weight, while Tirzepatide users showed even higher weight loss—up to 22% in some studies. Many patients also see improvements in blood pressure, cholesterol, and blood sugar levels. Results vary by individual, and the best outcomes occur when medication is combined with lifestyle changes.

Is a GLP-1 Medication Right for You?

These medications are typically prescribed for adults with a BMI of 30 or higher (obesity), or a BMI of 27 or higher with weight-related health conditions like diabetes, high blood pressure, or sleep apnea. They're also considered for patients who have made previous unsuccessful attempts at weight loss through diet and exercise alone. During your consultation, we'll evaluate whether you're a good candidate based on your health history and goals.

What to Expect During Treatment

GLP-1 medications are administered via a simple weekly injection that most patients can do at home. Treatment typically begins with a low dose that gradually increases over several weeks to minimize side effects and allow your body to adjust. Common side effects like mild nausea typically improve within the first few weeks. Our team provides guidance on managing any symptoms you experience.

The Importance of Comprehensive Care

While GLP-1 medications are powerful tools, they work best as part of a comprehensive approach. At Verve Health, we combine medication with lifestyle support including regular follow-up appointments to monitor progress, personalized nutrition guidance and meal planning, physical activity recommendations tailored to your abilities, and ongoing behavioral support and accountability.

Getting Started

If you're interested in learning more about whether GLP-1 medications might be right for you, schedule a consultation with our weight loss specialists. We'll work together to create a personalized plan that fits your lifestyle and goals. Your journey to better health starts with a conversation.